CJC-1295 (No DAC)

CJC-1295 (No DAC), commonly referred to scientifically as Modified GRF 1-29, is a tetrasubstituted analogue of Growth Hormone-Releasing Hormone (GHRH). Unlike its “With DAC” counterpart, this peptide lacks the Drug Affinity Complex, resulting in a significantly shorter half-life (approximately 30 minutes) that mimics the body’s natural pulsatile release of growth hormone. This modification improves resistance to enzymatic cleavage by DPP-IV, making it a highly effective tool for researching physiological growth hormone secretion patterns without the continuous stimulation associated with long-acting analogues.